Clinical scenarios of unexplained sperm DNA fragmentation and their management

Clinical scenarios of unexplained sperm DNA fragmentation and their management

Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for male fertility evaluation. While its detrimental implications on sperm function were extensively investigated, little is known about the actual indications for performing SDF analysis. This review delivers practice based recommendations on commonly encountered scenarios in the clinic. An illustrative descriptio...

Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for male fertility evaluation. While its detrimental implications on sperm function were extensively investigated, little is known about the actual indications for performing SDF analysis. This review delivers practice based recommendations on commonly encountered scenarios in the clinic. An illustrative descriptio...

Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Recent studies show that spermatozoal DNA integrity is essential for normal fertilization and transmission of paternal genetic information to the offspring. Additionally, fertilization and embryo development depend on the sperm DNA structure (1,2). Generally, while fertile men have high levels of sperm with intact DNA...

Sperm DNA fragmentation: laboratory and clinical aspects